Up-regulation of PCOLCE by TWIST1 promotes metastasis in Osteosarcoma

Conclusion: Our findings are the first to provide evidence that PCOLCE plays a critical role in promoting the lung metastasis of osteosarcoma, and this up-regulation of PCOLCE by TWIST1 may lead to a new therapeutic strategy to treat patients with metastatic osteosarcoma.

Source: Theranostics - June 13, 2019 Category: Molecular Biology Authors: Shang Wang, Li Zhong, Yin Li, Desheng Xiao, Ruhua Zhang, Dan Liao, Dongming Lv, Xin Wang, Juanfei Wang, Xianbiao Xie, Jing Chen, Yuanzhong Wu, Tiebang Kang Tags: Research Paper Source Type: research