A unique combination adjuvant modulates immune responses preventing vaccine-enhanced pulmonary histopathology after a single dose vaccination with fusion protein and challenge with respiratory syncytial virus.

This study suggests that combination CpG and MPL adjuvant in RSV subunit vaccination might contribute to priming protective immune responses and preventing inflammatory RSV disease after infection. PMID: 31163351 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31163351?dopt=Abstract

Source: Virology - May 27, 2019 Category: Virology Authors: Lee Y, Ko EJ, Kim KH, Lee YT, Hwang HS, Kwon YM, Graham BS, Kang SM Tags: Virology Source Type: research