A comparison of neuropsychological function between monozygotic twins with neurofibromatosis, type 1: A case report.

Conclusions: Intrapair similarities and differences on neuropsychological assessment were found between monozygotic twins with NF-1. Primary deficits were suggestive of a frontal-subcortical pattern and could be consistent with remote neuroimaging. When differences did occur, performance was typically better for Twin A, who had also showed greater improvement on neuroimaging. Implications and directions for future research are discussed. Specifically, this case demonstrates the need for inclusion of neuropsychological assessment in studies of larger cohorts of monozygotic twins with NF-1 and correlation of neuropsychological findings with neuroimaging and postzygotic mutations. PMID: 31154935 [PubMed - as supplied by publisher]
Source: The Clinical Neuropsychologist - Category: Psychiatry & Psychology Authors: Tags: Clin Neuropsychol Source Type: research