New Introduction of a Very Virulent Infectious Bursal Disease Virus in New York, USA.

New Introduction of a Very Virulent Infectious Bursal Disease Virus in New York, USA. Avian Pathol. 2019 Jun 03;:1-20 Authors: Michel LO, Kimber ML, Jackwood DJ Abstract Bursa tissue samples from a pullet flock in New York State that was experiencing immune suppression related disease were sent to our laboratory in 2018. A very virulent infectious bursal disease virus (vvIBDV) was identified in those samples through molecular and pathogenicity studies and designated 1/chicken/USA/1054NY/18. Phylogenetic analyses of the hypervariable VP2 nucleotide sequence region indicated that this strain belonged to genogroup 3 which comprises the vvIBDV. Partial sequence data of the VP1 gene indicated this virus also had a VP1 typical of vvIBDV. While vvIBDV have previously been identified in the United States in California and Washington State, the 1054NY vvIBDV was most closely related to isolates from Ethiopia, suggesting it is a new introduction into the U.S. The 1054NY vvIBDV was used to challenge four-week old specific-pathogen-free (SPF) layer chicks where it caused 100% morbidity and 68.7% mortality within four days. Upon necropsy, gross pathological findings in infected SPF birds included small yellowish colored bursas, some with hemorrhages on the serosal and mucosal surfaces. Microscopic lesions included inflammation, severe lymphocyte necrosis, atrophy of the follicles and follicular depletion of lymphocytes. Research Highlights: A very virulent infectious...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research

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In this study, we detected for just the second time a SINV infection in a diseased wild bird (common wood pigeon) from Central Europe. SINV was isolated by cell culture and the complete SINV genome sequence was determined. Phylogenetic analyses revealed a close affiliation to SINV genotype I with a high similarity to human isolate sequences from Finland, Sweden and Russia. The isolate was genetically distinct from the first avian isolate suggesting the circulation of at least two different SINV strains in Germany.In order to reveal the infection frequency in SINV positive mosquito regions 749 bird blood samples were assaye...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Publication date: Available online 11 October 2019Source: Saudi Journal of Biological SciencesAuthor(s): Rahat Andleeb, Asma Ashraf, Saima Muzammil, Shabana Naz, Farkhanda Asad, Tayyaba Ali, Rida Rafi, K.A. Al-Ghanim, F. Al-Misned, Z. Ahmed, Shahid MahboobAbstractThe study was implemented to actuate the qualitative and quantitative phyto constituents of Iresine herbstii extracts and its antiviral efficacy against avian ND virus. Among four tested solvents, the ethanolic extract of Iresine herbstii revealed the presence of highest quantity of all tested phytochemicals while petroleum ether extract showed the least. Folin-Ci...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Authors: Tolan HEM, El-Sayed WA, Tawfek N, Abdel-Megeid FME, Kutkat OM Abstract New 1,2,3-triazole glycosides and 1,2,4-thioglycosides incorporating a substituted pyrimidinedione ring system were synthesized via click dipolar cycloaddition and heterocyclization of hydrazine-1-carbodithioate derivatives, respectively. The sugar hydrazine derivatives linked aminodimethyluracil were also prepared. In addition, the oxadiazoline substituted with acyclic sugar moieties linked to the pyrimidinedione as acyclic nucleoside analogs were synthesized. The antiviral activity of the synthesized compounds against avian influenza ...
Source: Nucleosides, Nucleotides and Nucleic Acids - Category: Biochemistry Tags: Nucleosides Nucleotides Nucleic Acids Source Type: research
FRIDAY, Oct. 11, 2019 -- The risk for hospitalization with pandemic influenza is higher for patients with type 2 diabetes than for those without type 2 diabetes, according to a study published online Oct. 6 in the Journal of Internal Medicine. Paz...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Publication date: Available online 10 October 2019Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Marc. K. Kouam, Herman M.F Biekop, Bridget Katte, Alexis TeguiaAbstractSalmonella infections in poultry farms are overlooked in many African countries; yet these infections are mostly zoonotic with impact on both poultry industry and public health. Considering the impact of Salmonella in laying hens, and the role of laying hens as a source of Salmonella outbreak in human, knowledge of the status of Salmonella on laying hen farms as well as the factors influencing the presence of Salmonella is imp...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Epidemics of seasonal influenza caused by H1N1pdm09, H3N2, and type B viruses occur throughout the world. Sporadic human H5 and H7N9 virus infections are also reported in particular regions. To treat influenza patients effectively with antivirals, sensitive and broad-reactive influenza rapid diagnostic tests (IRDTs) are required. Here, we tested the sensitivity of 23 IRDTs during the 2018–2019 influenza season for their ability to detect H1N1pdm09, H3N2, H5N1, H5N6, H7N9, and Victoria- and Yamagata-lineage type B viruses. All IRDTs detected all influenza A and B viruses tested but with different sensitivities. Severa...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
e Yi Tian Poultry farmers face a dual risk when mutant avian influenza (AI) virus exhibits zoonotic characteristics. A/H5N1 and A/H7N9 are two principal strains of the AI virus that have captured public attention in recent years, as they have both been reported and can infect poultry and humans, respectively. Previous studies have focused either on poultry farmers’ risk perception and biosecurity preventive behaviors (BPBs) against A/H5N1 infection with poultry, or on their risk perception and personal protective behaviors (PPBs) against human infection with A/H7N9, even though these two strains often appea...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Sanderlings, red-headed woodpeckers and great gray owls are just a few of the North American bird species projected to be threatened by climate change in the coming decades, according to the latest assessment depicting an increasingly dire situation for the continent’s avian wildlife. “Two thirds of birds in North America are at risk from climate change, to large range losses, potentially extinction, and this is especially so if we continue on the current trajectory,” says Brooke Bateman, senior climate scientist for the National Audubon Society, which carried out the report. The October 10 report, titled...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized climate change onetime Source Type: news
France has detected a low-pathogenic H5 bird flu virus on a duck farm in the centre of the country, the Paris-based World Organization for Animal Health (OIE) said on Thursday, citing a report from the French agriculture ministry.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
AbstractVeterinary vaccines need to have desired characteristics, such  as being effective, inexpensive, easy to administer, suitable for mass vaccination and stable under field conditions. DNA vaccines have been proposed as potential solutions for poultry diseases since they are subunit vaccines with no risk of infection or reversion to virulence. DNA vaccines can be utilized for simultaneous immunizations against multiple pathogens and are relatively easy to design and inexpensive to manufacture and store. Administration of DNA vaccines has been shown to stimulate immune responses and provide protection from challen...
Source: Veterinary Research - Category: Veterinary Research Source Type: research
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