Antidepressants and the Risk of Hemorrhagic Stroke in the Elderly: a Nested Case –Control Study

ConclusionOur study shows that the use of medications inhibiting serotonin and/or noradrenaline reuptake increases the risk of HS in patients aged 65  years and older and that the risk varies across individual ADs.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research

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OBJECTIVE: The current study examined suicide-related disclosure intentions in LGBTQ  + youth, and the associations between reporting of lifetime experiences of minority stress and intentions to disclose suicidal thoughts. METHOD: A sample of 592 LG...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
[Abstract unavailable] Language: en...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
One of my former residents texted this info to me with the EKGs:" I have here a 50 something-year-old female with multiple stents who presents with a concerning pain history. Pain relief with nitroglycerin, and I am starting a nitroglycerin drip. " I ’m worried about a hyperacute RCA infarct. " There is no old ECG available." I have to transfer for PCI, and am wondering if I should give thrombolytics first. "Here is the initial ECG:Inferior STE less than 1 mm, with reciprocal inverted T-wave and STD in aVL  I recorded this one 15 minutes later:Now with straightening of the...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Conclusion:Transfer for PCI without thrombolytics is best if PCI at receiving facility can be done in less than 120 minutes from first medical contact, or less than 90 minutes from STEMI diagnosis in first ED.Thrombolytics prior to Transfer to a PCI capable facility, then rescue PCI if no reperfusion for STEMITRANSFER AMI(Cantor et al. 2009).High risk STEMI: BP less than 100, HR greater than 100 Killip class II, III, ST depression of at least 2 mm in precordial leads, ST elevation in right precordial leads (right ventricular MIAll patients get TNK-tPA.80-90% received clopidogrel 300 mg (75 mg for age over 75).Enox...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Conclusion The impact of sepsis on the gut is manifold, e.g., sepsis mediated alteration of the gut-blood barrier and increase in the intestinal permeability, which may correlate with the phenomena of bacterial translocation and lymphatic activation (“toxic-lymph”). Systemic consequences of sepsis are widespread and concern to the coagulative system, the microbiome as well as enzymes, such as pancreatic proteases, MMPs and IAPs. Nevertheless, the therapeutic approaches for modulating the mucosal immune system are still rarely effective in daily routine. Recent published studies showing that treatment with FMT,...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 9 November 2017 Source:Pharmacology & Therapeutics Author(s): Roberto Federico Villa, Federica Ferrari, Antonio Moretti Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively affects survivals' functional outcome, response to rehabilitation and quality of life. Approximately, one-third of them are affected by post-stroke depression (PSD), making it a serious social and public health problem and anti-depressant preventive and curative therapies worth investigating. However, a two-way association between depression and stroke has been also established...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Hereditary hemorrhagic telangiectasia (HHT) is characterized by frequent severe bleeding, particularly epistaxis, and life-threatening complications including stroke, brain abscess and heart failure. The psychological impact of HHT is not known. We conducted this cross sectional study to determine the prevalence of depression and post-traumatic stress disorder (PTSD) related to HHT.
Source: Thrombosis Research - Category: Hematology Authors: Tags: Full Length Article Source Type: research
WEDNESDAY, Feb. 22, 2017 -- Survivors of the most deadly type of stroke face a higher risk for developing depression and dementia, new research suggests. Often called " bleeding strokes, " hemorrhagic strokes occur when a blood vessel ruptures and...
Source: Drugs.com - Daily MedNews - Category: Journals (General) Source Type: news
This study builds on preliminary findings from the first phase of the INTERSTROKE study, which identified ten modifiable risk factors for stroke in 6,000 participants from 22 countries. The full-scale INTERSTROKE study included an additional 20,000 individuals from 32 countries in Europe, Asia, America, Africa and Australia, and sought to identify the main causes of stroke in diverse populations, young and old, men and women, and within subtypes of stroke. To estimate the proportion of strokes caused by specific risk factors, the investigators calculated the population attributable risk for each factor (PAR; an esti...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
I’m not interested in lengthening your lifespan. I want to increase your “health span”… the length of time you feel energized and ready to take on the world. And an important part of your “health span” is your emotional well-being. The brain chemical serotonin plays a big part in keeping you emotionally balanced. That’s why it’s called the “happy hormone.” What Does Serotonin Levels Affect? Serotonin does a lot more than keep you in a good mood. Your serotonin levels affect your: Energy levels Sex drive Memory Weight and appetite Sleep Low Serotonin Levels Can...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health Source Type: news
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