The Role of 18F-FDG PET/CT in the Assessment of Patients with Intravascular Large B-Cell Lymphoma

Conclusions: 18F-FDG PET/CT may contribute to the diagnosis in patients with suspected IVLBCL by providing precise biopsy sites when involvement of bone marrow, liver, spleen, and lungs occur. It also could provide valuable information as follow-up measurement for prognosis evaluation of IVLBCL. Fig. 1 Eight cases of FDG-PET/CT MIP images showed hepatosplenomegaly and hypermetabolic activity in the liver, spleen, and BM in varying degrees. (A) A 60-year-old woman was verified by BM biopsy. (B) A 58-year-old woman showed focal uptake in both caput humeri and underwent biopsy in the left one (black arrow) (C) A 47-year-old man showed diffuse skin FDG uptake and get a random biopsy. (D) A 33-year-old woman who showed diffuse lung FDG uptake and focal uptake in left lung nodules. Histopathology revealed by TBLB. (E) A 71-year-old man got liver biopsy in the focus of increased uptake in the right hepatic lobe (black arrow). (F) A 56-year-old woman showed the diffuse uptake in bilateral kidneys, which were significantly enlarged, and underwent renal biopsy. (G) A 61-year-old woman got adrenal biopsy on the right (black arrow), given bilateral adrenals hypertrophy with increased uptake. (H) A 45-year-old woman showed increased focal uptake in the left lobe of the thyroid (black arrow) and lymph nodes (black triangle). Histopathology by thyroidectomy indicated only nodal involvement, with the thyroid pathology attributed to nodular goiter. Focal uptake in the lymph node was reactive ...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Lymphoma / Leukemia / Myeloma Posters Source Type: research