Non-canonical TSHR signaling activation increases cell mobility and dedifferentiation of thyroid cancer

Conclusions: Our results elucidate non-canonical activation of TSH-TSHR signaling and its role in increasing cell mobility and dedifferentiation in thyroid cancer through crosstalk with PI3K/AKT/mTOR signaling.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Feng, F., WU, S., Wang, H. Tags: Oncology, Basic and Translational (Basic Science) II Source Type: research