Genes located in Y-chromosomal regions important for male fertility show altered transcript levels in cryptorchidism and respond to curative hormone treatment

ConclusionOur findings implicate Y-chromosomal genes, includingUSP9Y, UTY, TXLNGY, RBMY1B, RBMY1E, RBMY1J and TSPY4, some of which are known to be important for spermatogenesis, in the curative hormonal treatment of cryptorchidism-induced infertility.

Source: Basic and Clinical Andrology - June 2, 2019 Category: Urology & Nephrology Source Type: research