Keratinocyte Growth Factor-2 Stimulates P-glycoprotein Expression and Function in Intestinal Epithelial Cells.

In conclusion, our findings define the post-translational and transcriptional mechanisms underlying stimulation of Pgp function and expression by KGF2 that may contribute to the beneficial effects of KGF2 in intestinal inflammatory disorders.
PMID: 23328208 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - January 17, 2013 Category: Physiology Authors: Saksena S, Priyamvada S, Kumar A, Akhtar M, Soni V, Anbazhagan AN, Alakkam A, Alrefai WA, Dudeja PK, Gill RK Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research