Epigenetically regulated imprinted gene expression associated with IVF and infertility: possible influence of prenatal stress and depression

ConclusionsIn combination, the studies discussed, as well as two recent projects of our own on placental imprinted gene expression, suggest that lower birthweights in IVF infants are secondary to a combination of exposures including the infertility and prenatal stress that couples undergoing IVF are experiencing. The work highlighted herein emphasizes the need for appropriate control populations that take infertility into account and also for consideration of prenatal psychosocial stressors as confounders and causes of variation in IVF infant outcomes.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research

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Conditions:   Infertility, Female;   Anxiety State;   Depression;   Quality of Life;   Sexual Function and Fertility Disorders Intervention:   Other: Filling out the forms including IDAS-II, BAI, SF-36 and FSFI Sponsors:   Bahceci Health Group;   Uskudar University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 14 October 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Marjan Torabi, Ashraf Kazem, Mahshid AbdishahshahaniAbstractObjectiveThe aim of this study is to validate the edited version of FAS for the purpose of couples undergoing ART.Study designIn this cross-sectional study, the validity of the revised version of the FAS questionnaire was assessed by testing it on 212 couples volunteered to undergo ART. The revised version comprises 12 items from the original FAS version and 6 items added based on a survey interview conducted on infertile coup...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
I am an experienced OB/GYN, well-versed in obstetrics, infertility, gynecology, surgery and — yes — menopause, or so I thought. So why was I so blindsided by my own menopause transition? I thought I was going through burnout, with anxiety, anger, mood swings, irritability, and depression. I was at a point in my career as […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions OB/GYN Source Type: blogs
Depression in patients with infertility often goes undiagnosed and untreated. The Patient Health Questionnaire-9 (PHQ-9) and its ultra-brief version (i.e. PHQ-2) are widely used measures of depressive symptoms...
Source: Reproductive Health - Category: OBGYN Authors: Tags: Research Source Type: research
Authors: Kalaitzaki AE, Mavrogiannaki S, Makrigiannakis A Abstract The aim of this prospective, cross-sectional study was to examine the protective and risk psychological factors associated with the successful outcome of In vitro fertilisation (IVF). Various psychological factors that may affect the IVF outcome were measured to a sample of 61 infertile women (mean age 37.2 ± 4.4), who started their first or consecutive IVF treatment cycle in an IVF Unit in Greece. Over half of the participants (50.8%) became pregnant. A binary logistic regression analysis (stepwise) was conducted on pregnancy a...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
AbstractLittle is known about disclosure of diagnosis to males with Klinefelter syndrome (KS) diagnosed before birth or during childhood, especially in Asian context. Insufficient preparation for disclosure communication could lead to the child ’s depression, anxiety, or disrupted self-esteem. This is an interventional and qualitative interview study with a brief self-reported survey. The study consists of three phases. In phase I, adults with KS were asked about their experiences and viewpoints toward KS disclosure and diagnosis through individual interviews. In phase II, unaffected adolescent males were given infor...
Source: Journal of Community Genetics - Category: Genetics & Stem Cells Source Type: research
The objective of this study was to identify barriers to counseling for women with infertility in a clinic with embedded psychological support; and determine if those barriers were dependent upon screening scores for anxiety or depression.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
To investigate the anxiety scores and depression scales of infertile women that applied to Bah çeci Fulya IVF Center for elective frozen blast embryo transfer between February 26, 2019, and April 18, 2019.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Oral session Source Type: research
Rheumatoid arthritis (RA), an auto-immune disease, shows a consecutive stimulus of proinflammatory cytokines, following a wide range of pathophysiological reactions, leading to increased synthesis of acute phase proteins like C - reactive protein (CRP) and dysregulation in levels of immunomodulatory soluble Human Leukocyte Antigen-G (sHLA-G) molecule. Toxic effects of Methotrexate (MTX), a major component of disease-modifying antirheumatic drugs (DMARDs), can cross blood-testis-barrier and can induce changes in sperm for men of reproductive age group like germ cell apoptosis, mutagenic changes in germline cells, permanent ...
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster session Source Type: research
In the field of reproductive endocrinology and infertility (REI), physician online presence plays a large marketing role with success rates and procedures reported on clinic/hospital websites1 and patient assessments on physician rating sites. Compared to other specialties, REI clinics place a strong emphasis on optimizing patient-centered care in order to enhance their experience, increase treatment compliance and patient wellbeing while minimizing anxiety and depression during their often extended treatment cycles2.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Oral session Source Type: research
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