Prx1 Expressing Cells Are Required for Periodontal Regeneration of the Mouse Incisor

In conclusion, pnPRX1+ cells are present within the continuously regenerating PDL of mouse incisor, and at such location they contribute to post-natal periodontal development and regeneration. Since this study further reports the presence of PRX1 expressing cells within human periodontal ligament, we suggest that studying the mouse periodontal pnPRX1+ cells may provide significant information for the development of novel and more effective periodontal regenerative therapies in humans.
Source: Frontiers in Physiology - Category: Physiology Source Type: research