Immunotherapy improves sleep and cognitive impairment in anti-IgLON5 encephalopathy

Autoimmune encephalopathy associated with immunoglobulin G (IgG) autoantibodies binding to IgLON5 is characterized by a sleep disorder that includes sleep-disordered breathing and parasomnia, accompanied by gait disturbance, bulbar symptoms, dysautonomia, and cognitive decline.1 The effect of immunotherapy in patients with anti-IgLON5 disease remains unclear.

Source: Neurology Neuroimmunology and Neuroinflammation - May 20, 2019 Category: Neurology Authors: Brunetti, V., Della Marca, G., Spagni, G., Iorio, R. Tags: Autoimmune diseases, Encephalitis, Parasomnias Clinical/Scientific Notes Source Type: research