Does time equal vision in the acute treatment of a cohort of AQP4 and MOG optic neuritis?

Conclusions In this retrospective study of ON with AQP4 and MOG-IgG, even a 7-day delay in IVMP initiation was detrimental to vision. These results highlight the importance of early treatment for the long-term visual recovery in this group of patients. A prospective, multicenter study of the effects of timing of IVMP is currently underway. Classification of evidence This study provides Class IV evidence that hyperacute treatment of AQP4 and MOG-ON with IVMP increases the chance for good visual recovery (20/20 vision) and that even a greater than 7-day delay in treatment is associated with a higher risk for poor visual recovery.

http://nn.neurology.org/cgi/content/short/6/4/e572?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - May 20, 2019 Category: Neurology Authors: Stiebel-Kalish, H., Hellmann, M. A., Mimouni, M., Paul, F., Bialer, O., Bach, M., Lotan, I. Tags: Devic's syndrome, Optic neuritis; see Neuro-ophthalmology/Optic Nerve Article Source Type: research