Risk of suicide attempt associated with isotretinoin: a nationwide cohort and nested case-time-control study - Droitcourt C, Nowak E, Rault C, Happe A, Le Nautout B, Kerbrat S, Balusson F, Poizeau F, Travers D, Sapori JM, Lagarde E, Rey G, Guillot B, Oger E, Dupuy A.

BACKGROUND: Isotretinoin is the only effective treatment for severe acne. An isotretinoin-related suicide risk is still debated and under scrutiny by regulatory agencies. Our objectives were: to assess the risk of suicide attempt before, during and after i...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

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This study aimed to evaluate the quality of life, depression, anxiety,...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
ConclusionWe found that neither isotretinoin nor antibiotic treatment affected the levels of depression, anxiety, and suicide in acne patients. Moreover, both isotretinoin and antibiotic treatment were shown to improve the quality of life, social anxiety, and obsessive –compulsive symptoms in acne patients. However, clinicians should be careful about psychiatric side effects in patients using isotretinoin. Further studies with a larger number of cases and with a longer follow-up period are needed to investigate the complex effects of isotretinoin on the central nervous system.
Source: Pediatric Drugs - Category: Pediatrics Source Type: research
CONCLUSION: We found that neither isotretinoin nor antibiotic treatment affected the levels of depression, anxiety, and suicide in acne patients. Moreover, both isotretinoin and antibiotic treatment were shown to improve the quality of life, social anxiety, and obsessive-compulsive symptoms in acne patients. However, clinicians should be careful about psychiatric side effects in patients using isotretinoin. Further studies with a larger number of cases and with a longer follow-up period are needed to investigate the complex effects of isotretinoin on the central nervous system. PMID: 31175639 [PubMed - as supplied by publisher]
Source: Paediatric Drugs - Category: Pediatrics Authors: Tags: Paediatr Drugs Source Type: research
The teenage years are hard on kids’ sense of identity and self-esteem, especially as their bodies and minds are changing and growing at a rapid rate. As a parent, it may feel like you are jumping through mental and emotional hoops, doing your best to build up your child while still maintaining discipline. However, adolescents who struggle with body dysmorphic disorder (BDD) may need more help than most parents may realize. Body Dysmorphic Disorder Strikes At A Vulnerable Age Body dysmorphic disorder is a mental disorder that leads individuals to constantly think about their perceived appearance flaws. These flaws may...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Eating Disorders Parenting Perfectionism Adolescence Body dysmorphia Body Image Teenagers Source Type: blogs
Conclusion: Some patients with psychiatric syndromes and increased ANA titers may suffer from psychiatric variants of SLE, even if the American College of Rheumatology criteria for SLE are not met. Whether the psychiatric symptoms in our patient represent a prodromal stage with the later manifestation of full-blown SLE or a subtype of SLE with isolated CNS involvement remains unclear. Regardless, early diagnosis and initiation of immunosuppressive treatment are essential steps in preventing further disease progression and organ damage. Intrathecal ANAs with extractable nuclear antigen differentiation may be a more sensitiv...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
 Valentine’s Day comes but once a year and is experienced in different ways depending on your age, gender, or whether or not you are in a relationship. Not surprisingly, mental health status plays a role in the way this holiday is experienced, as well. Listen in as our hosts play the ever-popular Two Truths and a Lie to describe all they went through being depressed while dating. SUBSCRIBE &REVIEW “You don’t tell a girl, ‘Don’t take that pill.’” – Michelle Hammer   Highlights From ‘Bipolar, Schizophrenia, Depression, and Valentine’s Day’...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: A Bipolar, A Schizophrenic, and a Podcast General Relationships Schizophrenia Source Type: blogs
ConclusionsThe association of isotretinoin exposure with prenatal developmental toxicity is well established. Though numerous reports also link isotretinoin treatment with psychiatric side effects, this association remains controversial. The extent to which isotretinoin influences pediatric and adult development and cognition, and whether and why certain individuals may be susceptible to psychiatric side effects, remains to be clarified.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research
Amanda began the process overweight, depressed, struggling with energy, muscle and joint pains, pre-diabetic, hypertensive, and with polycystic ovary syndrome, reliant on numerous medications even in her 20s and early 30s. As you can see now, after starting with the Wheat Belly 10-Day Grain Detox, she is now slender and free of ALL her health problems and off ALL her medications. “The pic on the left is me in my 20’s, 27 to be exact. This was before I ever started my journey. “That smile was masking physical and emotional pain, suicidal ideation, PCOS, depression, hypothyroidism, ADD symptoms, fibromyalg...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates blood pressure diabetes fibromyalgia grain-free grains hypertension Inflammation joint pain polycystic ovary pre-diabetes pros undoctored Weight Loss wheat belly Source Type: blogs
For many skin-pocked teenagers and adults, the frustration and shame of uncontrolled acne has been linked to a higher risk for clinical depression and suicide or suicidal thoughts.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Background: Isotretinoin (ISO) is a synthetic oral retinoid used mainly for the treatment of nodulocystic acne and some other dermatologic disorders. There have been reports of increased suicidal behavior with ISO, however there is no conclusive evidence supporting this.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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