The proportion of dementia attributable to common modifiable lifestyle factors in Barbados.
Conclusion: Using a largely theoretical model, the six modifiable lifestyle factors were estimated to be attributable to 50.9% of dementia cases in Barbados. Since the risk factors have much in common, any intervention that targets one of them could significantly reduce future dementia prevalence. PMID: 31093046 [PubMed]
(Oxford University Press USA) A new study soon to appear in the Faculty of Public Health's Journal of Public Health, published by Oxford University Press, suggests that air pollution and living in apartment buildings may be associated with an increased risk for dangerous conditions like heart disease, stroke, and type 2 diabetes. This paper is embargoed until midnight EST on June 25.
Contributors : Caiyan Zhang ; Yufeng ZhouSeries Type : Expression profiling by array ; Non-coding RNA profiling by arrayOrganism : Homo sapiensTo determine ceRNA transcribed during the PBMCs, we have employed whole genome microarray expression profiling as a discovery platform to identify ceRNA expression in PBMCs donated by T1DM (type 1 diabetes mellitus) patients and healthy volunteers.
Contributors : Caiyan Zhang ; Yufeng ZhouSeries Type : Non-coding RNA profiling by arrayOrganism : Homo sapiensTo determine miRNA transcribed during the PBMCs, we have employed whole genome microarray expression profiling as a discovery platform to identify miRNA expression in PBMCs donated by T1DM (type 1 diabetes mellitus) patients and healthy volunteers.
Purpose: To compare retinal pathology visualization in multispectral scanning laser ophthalmoscope imaging between the Spectralis and Optos devices. Methods: This retrospective cross-sectional study included 42 eyes from 30 patients with age-related macular degeneration (19 eyes), diabetic retinopathy (10 eyes), and epiretinal membrane (13 eyes). All patients underwent retinal imaging with a color fundus camera (broad-spectrum white light), the Spectralis HRA-2 system (3-color monochromatic lasers), and the Optos P200 system (2-color monochromatic lasers). The Optos image was cropped to a similar size as the Spectrali...
In this study, we aimed to evaluate the efficacy and safety of intravitreal conbercept in patients with treatment-naive neovascular age-related macular degeneration in real-life setting. Methods: Three consecutive intravitreal injections of conbercept following a pro re nata protocol. The main outcomes were the changes of Early Treatment Diabetic Retinopathy Study best-corrected visual acuity and central retinal thickness between the baseline and the 12th month. Results: Mean best-corrected visual acuity was improved from 39.39 ± 24.91 letters at the baseline to 44.26 ± 22.89 letters at the final follow-up (P
Purpose: To investigate the natural history of Stargardt disease over a multiyear follow-up. Methods: We reviewed medical records of Stargardt disease patients, with clinical diagnosis of Stargardt disease at a single institution, which was also supported by molecular diagnosis. All patients underwent best-corrected visual acuity, fundus photography, optical coherence tomography, and full-field electroretinography. Results: The study cohort consisted of 157 Stargardt disease patients aged 30.4 ± 1.1 years. Longitudinal analysis (mean follow-up: 3 years) showed a significant worsening of best-corrected visual...
Publication date: Available online 24 June 2019Source: Brain, Behavior, and ImmunityAuthor(s): Qiang Liu, Lingli Yan, Miaodan Huang, Haitao Zeng, Senthil Kumaran Satyanarayanan, Zhe Shi, Dingbang Chen, Jia-Hong Lu, Zhong Pei, Xiaoli Yao, Huanxing SuAbstractAlcoholism is a risk factor for the development of cognitive decline and dementia. Here we demonstrated that the glymphatic function in the brain was impaired by alcohol administration. Acute moderate alcohol administration substantially retarded and reduced the entry of subarachnoid cerebrospinal fluid (CSF) via the paravascular space into the cerebral parenchyma, thus ...
ConclusionInfectious diseases are one of the most common factorsto hospitalize diabetic patients (27.7%), most of whom had diabetic foot infections, pneumonia, and soft tissue abscess.
DiabetesMine reviews the new book " Blood Sugar in Check " that focuses on the mental and behavioral challenges of living with diabetes.
ConclusionsHaemodynamic, biochemical alteration and histopathological results suggest a cardioprotective protective effect of oral administration of AZE in isoproterenol induced cardiotoxicity.Graphical abstract