Is scanning for vasa previa important for singleton pregnancies that started as multiple conceptions?
Publication date: Available online 18 May 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Yaakov Melcer, Marina Pekar-Zlotin, Brian Wolf, Moshe Betser, Shira Dvash, Nataly Zilberman Sharon, Ron MaymonAbstractObjectivesVasa previa (VP) is a congenital placentation disorder in which fetal vessels run across the internal os of the cervix under the fetal presentation. This rare condition is associated with a high rate of perinatal morbidity and mortality when undetected before delivery. Roughly 85% of all cases of VP can be associated with one or more identifiable risk factors including in-vitro fertilization (IVF), multiple gestations, bilobed, succenturiate or low-lying placentas, and velamentous cord insertion (VCI). Recent evidence indicates the need for standardized prenatal targeted scanning protocols of pregnancies at risk of VP. The present study reports on pregnancies that began with multiple gestations but ended with a single fetus diagnosed with VP.Study DesignWe retrospectively collected and reviewed medical records from 2006-2018 of early multiple pregnancies that ended with a single fetus diagnosed with VP in our medical center, including three cases of twin gestation complicated by a vanishing twin and a case of multifetal reduction in triplet pregnancy. This retrospective cohort study was approved by our Institutional Clinical Research Committee.ResultsThe database search identified 50 pregnancies that started as multi...
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ConclusionsWomen with CP are at increased risk of preterm birth and other adverse pregnancy outcomes, suggesting that they deserve extra surveillance during antenatal care. Further studies, with information on type of CP and gross motor function, are warranted in order to better understand the association between CP and pregnancy outcome.
ConclusionsThe presence of ISUA was associated with a more than five times increased risk of intrauterine and perinatal death and with placental and cord complications. The high associated risk of adverse outcome justifies follow up with assessment of fetal wellbeing in the third trimester, intrapartum surveillance and preparedness for third stage of labor complications.
ConclusionWithin the limitations of the study, GBR with or without autogenous block graft may be an effective approach in augmenting horizontally deficient mandibular or maxillary ridges, before the placement of dental implants. However, more complications may be seen with the use of an autogenous block graft related to the donor sites.
Abstract Cell senescence seems to be an ambivalent biological phenomenon in many aspects. At the cellular level it is considered as an irreversible cell-cycle arrest commonly caused by the DNA damage. Senescent cells harbor a lot of impairments in various intracellular systems. Presence of senescent cells within tissues should ultimately lead to their malfunctioning. However, the interlink between cellular senescence and tissue/organismal functioning is far from always being unidirectional. The entangled and complex relationship between senescence and tissue-specific decidual differentiation of endometrial stromal...
CONCLUSIONS: These findings are the first to indicate that HT induces a nonreceptive endometrial milieu in the euthyroid state, which may underlie the detrimental effects of HT itself on embryo implantation. PMID: 31729993 [PubMed - in process]
ConclusionThis case is a rare phenomenon in which the dead fetus remained in the uterus for a long time after a neglected obstructed labor and uterine rupture.
ConclusionsMid ‐Trimester uterine artery resistance measured at 18‐22 weeks of gestation is a weak predictor of spontaneous preterm birth.
AbstractIntroductionPregnancy ‐related medical complications are associated with a 2‐ to 5‐fold increased risk of preterm birth (PTB), but the nature of this etiologic relationship in context with maternal factors remains poorly understood. Previous studies have generally treated maternal age as a confounder but overlooked its potential as an effect modifier, whereby the magnitude of the effect of complications on PTB could differ significantly across age groups. We investigated whether advanced maternal age (≥35 years) modified the association between pregnancy complications and PTB, and compared population attri...