Silver nanoparticles fabricated by reducing property of cellulose derivatives.

Silver nanoparticles fabricated by reducing property of cellulose derivatives. Drug Discov Ther. 2019;13(2):70-79 Authors: Suwan T, Khongkhunthian S, Okonogi S Abstract The aim of this study was to synthesize silver nanoparticles (AgNPs) by using cellulose derivatives as a reducing agent. Methyl cellulose (MC), hydroxy ethylcellulose (HEC), and hydroxypropyl methylcellulose (HPMC) were compared for their reducing property. HPMC presented the highest reducing power, with equilibrium concentration (EC) of 84.6 ± 4.5 µmol Fe2+/g, followed by MC and HEC, with the EC of 62.3 ± 1.4, and 38.1 ± 3.2 µmol Fe2+/g, respectively. Using these cellulose derivatives as a reducing agent and silver nitrate as a precursor in fabrication of silver nanoparticles (AgNPs), three cellulose-AgNPs, HEC-AgNPs, MC-AgNPs, and HPMC-AgNPs, were obtained. The cellulose-AgNPs showed different maximum absorptions confirming AgNPs spectra at 415, 425, and 418 nm, respectively. Reaction parameters such as pH, temperature, and period of reaction affected intensity of the maximum absorptions and size of AgNPs. Using 0.3% cellulose solution at pH 9 and reaction at 70°C for 90 min, the particle size of MC-AgNPs, HEC-AgNPs, and HPMC-AgNPs was 97.7 ± 2.4, 165.6 ± 10.6, and 51.8 ± 1.6 nm, respectively. AgNPs obtained from different cellulose derivatives and various preparation parameters possess different inhibition potential against Escherichia coli and Staphylococ...
Source: Drug Discoveries and Therapeutics - Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research