F47. Longitudinal Development of Social-Cognition Regions Covaries With Amygdala Volume in Children With Williams Syndrome

Williams syndrome (WS), typically characterized by hypersociability and non-social anxiety, is caused by hemideletion of ∼25 genes at chromosomal location 7q11.23. Previous evidence suggests alterations in the development of amygdala volume in children with WS compared to typically developing children. Here, we longitudinally studied the structural covariance of amygdala size with changes in gray-matter volume acros s the rest of the brain to explore development of networks from childhood/adolescence through early adulthood in WS.

Source: Biological Psychiatry - May 13, 2019 Category: Psychiatry Authors: Franchesca Kuhney, J. Shane Kippenhan, Tiffany Nash, Mbemba Jabbi, Michael Gregory, Leah Sorcher, Madeline Hamborg, Shannon Grogans, Philip Kohn, Daniel Eisenberg, Carolyn B. Mervis, Karen Berman Source Type: research