Retrospective evaluation of patient profiling and effectiveness of apremilast in an Italian multicentric cohort of psoriatic arthritis patients.

CONCLUSIONS: In our real-life analysis apremilast was mainly used in oligoarticular PsA carrying comorbidities leading to contraindications to biologics. Effectiveness and safety profiles were consistent with clinical trials. PMID: 31074721 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

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[East African] The Global Fund, the body that finances the world's HIV, tuberculosis (TB) and malaria programmes, has given Kenya Ksh42 billion ($420 million) to cover the intervening years to 2024.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Conclusion: Brentuximab vedotin increased the risk of certain AEs in lymphoma patients. PMID: 31955620 [PubMed - as supplied by publisher]
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
Publication date: Available online 20 January 2020Source: International Journal of PaleopathologyAuthor(s): Elizabeth A. Nelson, Jane E. Buikstra, Alexander Herbig, Tiffiny A. Tung, Kirsten I. BosAbstractAndean paleopathological research has significantly enhanced knowledge about the geographical distribution and evolution of tuberculosis (TB) in pre-Columbian South America. In this paper, we review the history and progress of research on ancient tuberculosis (TB) in the Andean region, focusing on the strengths and limitations of current approaches for the molecular detection of ancient pathogens, with special attention to...
Source: International Journal of Paleopathology - Category: Pathology Source Type: research
Publication date: March 2020Source: Epilepsy &Behavior, Volume 104, Part AAuthor(s): J. Eric Piña-Garza, William Rosenfeld, Kazunori Saeki, Vicente Villanueva, Harumi Yoshinaga, Anna Patten, Betsy Williams, Manoj MalhotraAbstractObjectiveThis post hoc analysis of six randomized, double-blind, Phase II and III studies evaluated efficacy and safety of adjunctive perampanel (2–12 mg/day) in adolescent patients (aged ≥ 12 to ≤ 17 years) with uncontrolled partial-onset seizures, with or without secondarily generalized (SG) seizures, or primary generalized tonic–clonic (PGTC) seizures.M...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Source: Infection and Drug Resistance - Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
Authors: Enciso-Vargas M, Alvarado-Ruíz L, Suárez-Villanueva AS, Macías-Barragán J, Montoya-Buelna M, Oceguera-Contreras E, Alvarado-Navarro A, Graciano-Machuca O Abstract Background: Psoriatic Arthritis (PsA) is a seronegative spondyloarthropathy frequently associated with psoriasis. Studies have shown different members of the KIR (Killer Immunoglobulin-like Receptor) gene family may act as potential susceptibility factors; however, data have been inconsistent or with a reduced sample size. Therefore, the objective of this investigation was to determine associations between KIR genes an...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Source: Risk Management and Healthcare Policy - Category: Health Management Tags: Risk Management and Healthcare Policy Source Type: research
ConclusionsAortic PVL is not uncommon after standard AVR. Operating surgeon, smaller body surface area, and female sex are risk factors for the development of this complication. These leaks are usually mild and generally have a benign course. However, the presence of mild to moderate or more severe aortic PVL may influence postoperative survival.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This study reports the validation of an enzyme-linked immunosorbent assay (ELISA) to detect bovine tuberculosis as an ancillary test to TST in dairy farms in Argentina.The estimated validation parameters were within the established requirements of the World Organization for Animal Health (OIE). The test demonstrated high repeatability, with coefficients of variation
Source: The Veterinary Journal - Category: Veterinary Research Source Type: research
BOSTON (CBS/CNN) – A new Chinese coronavirus, a cousin of the SARS virus, has infected more than 200 people since the outbreak began in Wuhan, China, in December. Boston’s Logan Airport is not currently screening passengers for the illness, a spokesman for Customs and Border Protection told WBZ-TV. That’s because there are no direct flights to Boston from that region. Additional health screening for coronavirus is in place at JFK Airport in New York, San Francisco International Airport and Los Angeles International Airport. The agency said the CDC has determined that coronavirus presents a low risk to the...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Coronavirus Logan Airport Source Type: news
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