The proton-coupled oligopeptide transporters PEPT2, PHT1 and PHT2 mediate the uptake of carnosine in glioblastoma cells.

In conclusion, our results demonstrate that the transporters PEPT2, PHT1, and PHT2 are responsible for the uptake of carnosine into glioblastoma cells and full function of all three transporters is required for maximum uptake.
PMID: 31073693 [PubMed - as supplied by publisher]

Source: Amino Acids - May 8, 2019 Category: Biochemistry Authors: Oppermann H, Heinrich M, Birkemeyer C, Meixensberger J, Gaunitz F Tags: Amino Acids Source Type: research