Evaluation of Sodium Hypochlorite Irrigant, Bingpeng Irrigant, and Fufang Bingpeng Irrigant as Endodontic Irrigants During Passive Ultrasonic Irrigation

The increased antibiotic resistant strains and side effects caused by synthetic drugs make it is a necessary to look for herbal alternatives. In the present study, the antimicrobial test, cell cytotoxicity test, cleaning test, q-PCR and high-throughput sequencing analyses were used to evaluate the potential of Fufang Bingpeng irrigant as root canal irrigant. Our in vitro results indicated that Fufang Bingpeng irrigant made a low minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for P. gingivalis ATCC 33277 (6.25% vs. 12.5%), P. intermedius ATCC 25611(6.25% vs. 6.25%), F. nucleatum ATCC 25286 (6.25% vs. 6.25%), E. faecalis ATCC 19433 (25% vs. 25%) and B. fragilis ATCC 25285 (12.5% vs. 12.5%), and could effectively remove the remaining debris and open dentinal tubules in root canals compared with NaCl irrigant (p
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research