Understanding the Pathophysiology to Improve the Therapeutic Management: Focus on Metabolic and Hormonal Comorbidities in Heart Failure

Heart failure (HF) is a leading cause of mortality and morbidity worldwide.1. Despite remarkable progress in the therapeutic management of HF, poor survival and high readmission rates are still observed.2 The presence of multiple comorbidities and, in particular, of metabolic and hormonal disorders, complicates the diagnostic and therapeutic management of HF patients and is responsible for a progression of the disease. Diabetes mellitus and insulin resistance are highly prevalent in HF patients and responsible for poor prognosis and for a typical HF phenotype.

Source: Heart Failure Clinics - May 10, 2019 Category: Cardiology Authors: Pasquale Perrone Filardi, Eduardo Bossone Tags: Preface Source Type: research