A headache with surprising outcome: first case of brucellosis caused by Brucella suis biovar 1 in Germany

AbstractIn July 2018, brucellosis was diagnosed in a German patient without a travel history to regions endemic forBrucella. Microbiological analysis, including whole-genome sequencing, revealedBrucella suis biovar 1 as the etiologic agent. Core-genome-based multilocus sequence-typing analysis placed the isolate in close proximity to strains originating from Argentina. Notably, despite a strong IgM response, the patient did not developBrucella-specific IgG antibodies during infection. Here, we describe the clinical course of infection, the extensive epidemiological investigations, and discuss possible routes of transmission.
Source: Infection - Category: Infectious Diseases Source Type: research