Clinical Impact of Circulated miR-1291 in Plasma of Patients with Liver Cirrhosis (LC) and Hepatocellular Carcinoma (HCC): Implication on Glypican-3 Expression

ConclusionsOur findings might indicate that miR-1291 exert oncogenic effects in hepatic carcinogenesis through positive regulation of GPC3 expression. We propose that GPC3 overexpression and its associated oncogenic effects are linked to the upregulation of miR-1291 in HCV patients.

http://link.springer.com/10.1007/s12029-019-00234-9

Source: Journal of Gastrointestinal Cancer - April 26, 2019 Category: Cancer & Oncology Source Type: research