Efficacy of virtual reality on balance and gait in multiple sclerosis. Systematic review of randomized controlled trials - Moreno-Verdu M, Ferreira-Sanchez MR, Cano-de-la-Cuerda R, Jimenez-Antona C.

INTRODUCTION: Multiple sclerosis (MS) is a neurodegenerative disease that causes gait abnormalities and a deficit in balance control in the vast majority of people affected by it. Virtual reality has been proposed as a complementary approach to conventiona...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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ConclusionsRecent findings from the fields of advanced neuroradiology and neurochemistry provide the promising prospect of demonstrating degenerative brain pathology in patients with MS before atrophy has installed. Although the overall level of evidence on the presented topic is still preliminary, this Review may pave the way for further longitudinal and multimodal studies exploring the relationships between the abovementioned measures, possibly leading to novel insights in early disease mechanisms and therapeutic intervention strategies.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research
AbstractThe personal health record (PHR) is a novel information technology in the domain of health. In recent decades, PHR has been employed as an emerging tool for the improvement of healthcare services for patients with chronic diseases. The application of PHR plays a significant role in healthcare provision for multiple sclerosis (MS) as a chronic disease. The present study aimed to identify the attributes of PHR for patients with MS. This was a systematic review performed in 2019. Scopus, ProQuest, Embase, PubMed, IEEE, and Web of Science databases as well as the Google Scholar were searched using a combination of keyw...
Source: Health and Technology - Category: Information Technology Source Type: research
Authors: Silveira C, Guedes R, Maia D, Curral R, Coelho R Abstract Multiple Sclerosis (MS) is a chronic disabling neuroinflammatory disease. Psychiatric manifestations have a high prevalence in MS patients and may worsen the illness progression and the patients' quality of life (QoL). Depression is a highly prevalent condition in MS patients, associated with poorer adherence to treatment, decreased functional status and QoL, and increased suicide risk. Diagnosis and treatment of this disorder is challenging because of symptom overlap. Other prevalent psychiatric comorbidities are anxiety disorders, bipolar disorder...
Source: Psychiatry Investigation - Category: Psychiatry Tags: Psychiatry Investig Source Type: research
Conclusions: In PwMS, muscle strength of particularly the weakest limb explains 20% to 30% of the variance across a number of lower-limb functional capacity tests. Thus, exercise programs should focus on increasing lower-extremity muscle mechanical function in PwMS and minimizing strength asymmetry between limbs.
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research
Publication date: Available online 6 December 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Monica R. Langley, Hyesook Yoon, Ha-Neui Kim, Chan-Il Choi, Whitney Simon, Laurel Kleppe, Ian R. Lanza, Nathan K. LeBrasseur, Aleksey Matveyenko, Isobel A. ScarisbrickAbstractMetabolic syndrome is a key risk factor and co-morbidity in multiple sclerosis (MS) and other neurological conditions, such that a better understanding of how a high fat diet contributes to oligodendrocyte loss and the capacity for myelin regeneration has the potential to highlight new treatment targets. Results demonstr...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Recent studies of cortical pathology in secondary progressive multiple sclerosis have shown that a more severe clinical course and the presence of extended subpial grey matter lesions with significant neuronal...
Source: Journal of Neuroinflammation - Category: Neurology Authors: Tags: Research Source Type: research
Disease-modifying therapies (DMTs) reduce relapse rates and disability progression for relapsing multiple sclerosis (MS). Although 25% to 30% of all US patients with MS are Medicare beneficiaries, limited information exists on this population. This is the first study using national Medicare data to (1) describe characteristics of patients with MS using DMTs, (2) estimate adherence to DMTs over a 1-year and 3-year follow-up, and (3) examine factors associated with DMT adherence.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research
To investigate the feasibility of conducting exoskeleton-assisted gait training (EAGT) and the effects of EAGT on gait, metabolic expenditure and physical function in individuals with multiple sclerosis (MS).
Source: Archives of Physical Medicine and Rehabilitation - Category: Rehabilitation Authors: Source Type: research
Long-term disability progression of pediatric-onset multiple sclerosis. McKay KA, Hillert J, Manouchehrinia A, et  al. Neurology 2019; Epub2019 May 15
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Commentary Source Type: research
CONCLUSIONS: The severity and duration of MS is a risk factor for rUTIs. Urodynamic risk factors are compatible with a lower contractile capacity in patients with rUTIs, while the existence of NLUTD would not imply any specific risk factor. PMID: 31797803 [PubMed - in process]
Source: Archivos Espanoles de Urologia - Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research
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