Fertility preservation in female cancer patients-state of the art.

Fertility preservation in female cancer patients-state of the art. Minerva Ginecol. 2019 Apr 15;: Authors: Findeklee S, Radosa JC, Takacs ZF, Hamza A, Sima RM, Solomayer EF, Sklavounos P Abstract Protecting fertility in the presence of cancer has become highly significant, as the desire to give birth to a child is increasingly postponed to later in life, and long-term survival with cancer has increased. A variety of fertility-preserving methods have been developed. To find them we did a literature search in Medline with the term "female fertility preservation in cancer" in December 2017. 2381 different publications were found. After screening the abstracts 78 publications in English, French or German language had been assessed as relevant (17 dealing with medicamentous approaches, 6 with surgical approaches, 15 with oocyte cryopreservation, 11 with ovarian tissue cryopreservation and 29 were review articles). In general, there are medicamentous (non-surgical) and surgical approaches. Medicamentous approaches comprise administration of GnRH-analogues during gonad toxic oncologic treatment, and cryopreservation of oocytes after ovarian stimulation. Surgical approaches comprise traditional methods of organ-saving surgery and ovarian transposition outside of the radiation portal as well as ovary cryopreservation as standard. It is important to inquire about a prospective desire to have children with premenopausal women with cancer and co...
Source: Minerva Ginecologica - Category: OBGYN Tags: Minerva Ginecol Source Type: research