Expression of immune checkpoint receptors Indoleamine 2,3 ‐dioxygenase and T cell Ig and ITIM domain in metastatic versus nonmetastatic choroidal melanoma

ConclusionThe expression of immune checkpoint receptor TIGIT is increased in primary uveal melanomas that seed metastases, and correlates with the expression of checkpoint receptor IDO. Both may be future targets for therapy.

Source: Cancer Medicine - April 15, 2019 Category: Cancer & Oncology Authors: Gustav St ålhammar, Stefan Seregard, Hans E. Grossniklaus Tags: ORIGINAL RESEARCH Source Type: research