Marijuana Users May Need More Sedation For Medical Procedures

(CNN) — People who regularly use cannabis may need two times the level of sedation required by nonusers when undergoing medical procedures, a small-scale study finds. Fentanyl, midazolam and propofol, three sedation drugs commonly used during endoscopic procedures, were compared in the research. With “continued increase in legalization and use of cannabis, the field of anesthesia and sedation needs further studies with greater depth,” wrote the authors of the study, published Monday in The Journal of the American Osteopathic Association. Wider use follows legalization Marijuana has gained popularity around the globe in recent years due, in part, to changing laws. Between 2007 and 2015, use of marijuana increased 43% in the United States, where an estimated 13.5% of adults use cannabis, according to a United Nations report. Meanwhile, cannabis use around the world was estimated to include 183 million people, or nearly 4% of the adult population, in 2015. How does increasing cannabis use affect medical care? Researchers at Community Hospital in Grand Junction, Colorado, explored one small area of medical care: sedation. They examined the medical records of 250 patients who received endoscopic procedures between January 1, 2016, and December 31, 2017 — years after the state legalized recreational marijuana in 2012. Comparing cannabis users to nonusers, they found that patients who reported smoking or using edibles on a daily or weekly basis required 14% m...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Marijuana Source Type: news

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Propofol provides a prominent sedation effect in colonoscopy. However, anesthesia and sedation induced with propofol in the elderly might result in cardiopulmonary complications, especially when it is combined...
Source: BMC Anesthesiology - Category: Anesthesiology Authors: Tags: Research article Source Type: research
Basavana Goudra, Preet Mohinder SinghSaudi Journal of Anaesthesia 2020 14(3):349-354 Providing sedation to patients undergoing gastrointestinal (GI) endoscopy is a controversial and emotive issue. The mainstay of sedation is propofol, whose administration is within the sole jurisdiction of anesthesia providers, at least in the USA. Attempts have been made to seize the authority by the GI community. One of the first attempts was the use of the prodrug of propofol –fospropofol. However, as the drug has a similar adverse effect profile as propofol in terms of respiratory depression, the FDA did not approve its use by p...
Source: Saudi Journal of Anaesthesia - Category: Anesthesiology Authors: Source Type: research
ConclusionsFC combined with US and digital rectal examination is a good and promising non-invasive screening test for detecting colorectal polyps in children with isolated and sporadic rectal bleeding.
Source: Italian Journal of Pediatrics - Category: Pediatrics Source Type: research
Conditions:   Moderate Sedation;   Colonoscopy Interventions:   Drug: flumazenil;   Drug: Placebos Sponsor:   National Taiwan University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The mounting pressure on the Australian healthcare system is driving a continual exploration of areas to improve patient care and access and to maximize utilization of our workforce. We hypothesized that there...
Source: Human Resources for Health - Category: Health Management Authors: Tags: Research Source Type: research
CONCLUSIONS: The addition of midazolam 0.04 mg·kg as adjunct to propofol and opiate sedation for elective colonoscopy did not show evidence of any significant differences in recovery in the cognitive domain of the PostopQRS, overall quality of recovery as measured by the PostopQRS, or emergence and hospital discharge times. The use of midazolam should be determined by the anesthesiologist. PMID: 31922999 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research
AbstractProviding sedation for patients undergoing gastrointestinal (GI) endoscopy continues to be a debated topic in both anesthesia and gastroenterology circles. Sedation approaches are widely varied across the globe. While propofol administration is embraced by more endoscopists and patients, its administration evolves controversy. Whereas trained nurses and gastroenterologists are allowed to administer propofol for GI endoscopy sedation in Europe and Asia, it is the sole privilege of anesthesia providers in the USA. However, the costs of anesthesia providers are significant and threaten to derail the screening colonosc...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
Authors: Arican Ş, Dertli R, Dağli Ç, Hacibeyoğlu G, Koyuncu M, Topal A, Tuncer Uzun S, Asil M Abstract Background/aim; Ultrasonographic measurements of inferior vena cava (IVC) diameters and right ventricle (RV) volumes are important tools for the evaluation of intravascular volume. Current study investigates the association of IVC diameters and RV volumes before colonoscopy in prediction of post-anesthesia hypotension. Materials and methods; Seventy patients scheduled for colonoscopy were included in the study. Preoperatively, expirium (dIVC max) and inspirium (dIVC min) IVC diameters were measured usin...
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
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