Brain Network Analysis for Auditory Disease: A Twofold Study

Publication date: Available online 11 April 2019Source: NeurocomputingAuthor(s): Pei-Zhen Li, Ling Huang, Chang-Dong Wang, Chuan Li, Jian-Huang LaiAbstractTinnitus is the phantom perception of sound and can have negative effect on the quality of life. Sudden deafness is generally defined as sensorineural hearing loss of 30 dB or greater over at least three contiguous audiometric frequencies and within a three-day period, which is usually unilateral and can be associated with tinnitus. The exact pathogenesis of such auditory diseases is still unknown, and alterations in the functional connectivity of the brain network are suspected to involve one possible pathogenesis. Scalp electroencephalogram (EEG) analysis is a common approach to capture brain neural activity. This paper conducts a twofold study in terms of brain network analysis for auditory diseases based on EEG data. Specifically, the brain network is constructed in view of the phase lag index (PLI) between signals. The unsupervised study is first conducted via the unsupervised network community detection algorithm. The goal is to reveal the underlying characteristics of functional connectivity concerning subjects with and without auditory diseases from the brain network perspective. The second study is the supervised learning. A new strategy termed FBA (Features from Brain Areas) is proposed to abstract each brain network as a feature vector and the supervised classification method, i.e., Support Vector Machine (SVM) i...
Source: Neurocomputing - Category: Neuroscience Source Type: research

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Conclusion: The reduction of tinnitus in the current ABI subject may be attributable to partial peripheral reafferentation-induced deactivation of the parahippocampus-based tinnitus generator as well as the salience network. Further validation is required by the use of a follow-up study with a larger number of subjects.
Source: Otology and Neurotology - Category: ENT & OMF Tags: AUDIOLOGY Source Type: research
In conclusion, for the radiological assessment of TB fractures, the entire VA should be regarded as a part of the otic capsule, and delayed inner ear sequelae should be anticipated for retrolabyrinthine fracture lines that course into or through the VA. When considering treatment options in cases similar to the present, our findings suggest that surgical interventions targeting the eES (ES shunting/decompression procedures (31–33), which are used in MD with the intention to drain the hydropic endolymphatic fluid space, or to improve the fluid resorptive functions of the eES, respectively, most likely cannot work as p...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Abstract To investigate the application of inner ear 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging (MRI) in patients with sudden sensorineural hearing loss (SSNHL) accompanied by inner ear hemorrhage. A total of 1252 SSNHL patients who were admitted from January 2010 to April 2018 were included in the study. The patients' clinical features, complete blood counts, coagulation profiles, audiometry data, and MRI scans were retrospectively reviewed. Twenty-four patients had high labyrinth signals on inner ear 3D-FLAIR MRI (24/1252, 1.9%) that were diagnosed as inner ear hemorr...
Source: Ear, Nose and Throat Journal - Category: ENT & OMF Authors: Tags: Ear Nose Throat J Source Type: research
CONCLUSION: Compared with adult patients, adolescent patients with total-deafness SSNHL undergoing combination therapy may be less likely to have hearing recovery and the improvement of tinnitus. PMID: 30762471 [PubMed - as supplied by publisher]
Source: Acta Oto-Laryngologica - Category: ENT & OMF Authors: Tags: Acta Otolaryngol Source Type: research
AbstractObjectiveThe present study was conducted to compare the rates of recovery from idiopathic sudden deafness after the treatment with oral and intratympanic corticosteroids in both mono and combination therapies.Study designTriple-blind randomized clinical trial.SettingsTertiary referral hospital.Subjects and methodsA total of 112 patients who were admitted to the ENT emergency department randomly divided into three groups: an oral corticosteroid plus intratympanic placebo (systemic corticosteroid monotherapy group); an intratympanic corticosteroid plus oral placebo group (IT monotherapy group); and a combination ther...
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
This study enrolled 20 subjects with congenital SSD and 44 subjects with acquired SSD and examined the presence and characteristics of tinnitus in the groups. None of the 20 subjects with congenital SSD perceived tinnitus on the affected side, whereas 30 of 44 subjects with acquired SSD experienced tinnitus on the affected side. Additionally, there were significant positive correlations between tinnitus characteristics and the audiometric characteristics of the SSD. In accordance with the findings of the recent animal study, tinnitus was absent in subjects with congenital SSD, but relatively frequent in subjects with acqui...
Source: Hearing Research - Category: Audiology Authors: Tags: Hear Res Source Type: research
Objectives/Hypothesis: We identified the efficacy and appropriate target group for intratympanic steroid injections (ITS) in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Study Design: Retrospective case-control study. Methods: Fifty-five ears treated with concomitant ITS and systemic steroids and 165 ears without ITS treatment were identified. Each case had three controls matched according to the age, sex, and the presence of vertigo. Patients were divided into subgroups according to pure tone audiometric configuration and the levels of initial hearing loss. Hearing results and frequency-related hea...
Source: Otology and Neurotology - Category: ENT & OMF Tags: Sensorineural Hearing Loss & Tinnitus Source Type: research
Conclusions: Early inner ear inflammation in MWS primarily affects the high frequencies, beyond the range of standard otologic assessment tools. The HF-PTA is a sensitive tool to detect imminent hearing loss and monitor treatment response.
Source: Pediatric Rheumatology - Category: Rheumatology Authors: Source Type: research
Objective: We aimed to evaluate the prognostic factors for acute-onset tinnitus associated with unilateral idiopathic sudden sensorineural hearing loss (ISSNHL) and to assess the relationship between these factors and the final recovery. Methods: A total of 770 patients with unilateral ISSNHL were enrolled retrospectively and their medical records reviewed. Patients were classified into two groups according to the presence of acute-onset tinnitus at the initial examination. Patient characteristics and the results of pure-tone audiometry were compared between the two groups initially and 3 months later. Results: A total of ...
Source: Audiology and Neurotology - Category: Audiology Source Type: research
Abstract The aim of the study was to evaluate mental distress and health-related quality of life in patients with bilateral partial deafness (high-frequency sensorineural hearing loss) before cochlear implantation, with respect to their audiological performance and time of onset of the hearing impairment. Thirty-one patients and 31 normal-hearing individuals were administered the Beck Depression Inventory (BDI), the State-Trait-Anxiety-Inventory (STAI) and the World Health Organization Quality of Life-BREF questionnaire (WHOQOL-BREF). Patients also completed the Nijmegen-Cochlear-Implant-Questionnaire (NCIQ), a to...
Source: European Archives of Oto-Rhino-Laryngology - Category: ENT & OMF Source Type: research
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