Signs and symptoms of the postictal period in epilepsy: A systematic review and meta-analysis

Publication date: May 2019Source: Epilepsy & Behavior, Volume 94Author(s): Ann Subota, Sundus Khan, Colin B. Josephson, Sofiya Manji, Sara Lukmanji, Pamela Roach, Samuel Wiebe, Jeffrey Buchhalter, Paolo Federico, G. Campbell Teskey, Diane L. Lorenzetti, Nathalie JettéAbstractObjectiveThe postictal period has many physical, behavioral, and cognitive manifestations associated with it. These signs and symptoms are common, can be quite debilitating, and can have a continued impact long after the seizure has ended. The purpose of this systematic review was to quantify the occurrence of postictal signs and symptoms, along with their frequency and duration in persons with epilepsy.MethodsCochrane Database of Systematic Reviews, CINAHL, EMBASE, MEDLINE, PsycINFO, Web of Science, and Scopus were searched from inception to November 29, 2017. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting standards were followed. Search terms included subject headings and text words such as convulsion, epilepsy, seizure, postictal, post seizure, seizure recovery, seizure end, Todd's paresis, and Todd's paralysis. Standardized forms were used to collect various study variables. Abstract and full-text review, data abstraction, and quality assessment were all done in duplicate. Study heterogeneity was assessed using the I-squared test, and a random effects model was used to determine estimates. Publication bias was evaluated using funnel plots.ResultsFrom 7811 ab...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research