Serum and CSF neurofilament light chain levels in antibody-mediated encephalitis

In conclusion, NfL levels are significantly in creased in the serum of patients with antibody-mediated encephalitis, independently of the MRI/CSF inflammatory profile. These findings support the presence of ongoing axonal damage and suggest the co-occurrence of different mechanisms for neuronal/axonal involvement in antibody-associated CNS syndr omes.
Source: Journal of Neurology - Category: Neurology Source Type: research