NMR metabolomics reveals effects of Cryptosporidium infections on host cell metabolome

ConclusionThis approach will spearhead our understanding of theCryptosporidium-host metabolic exchange and provide novel targets for tackling this deadly parasite.
Source: Gut Pathogens - Category: Microbiology Source Type: research

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Publication date: Available online 17 July 2019Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Lívia M. Alves, Heber L.S. Barros, José M.R. Flauzino, Pedro H.G. Guedes, Janser M. Pereira, Ricardo Toshio Fujiwara, Tiago W.P. Mineo, José R. Mineo, Ronaldo J. de Oliveira, João M. Madurro, Ana G.Brito-MadurroAbstractToxoplasma gondii is an intracellular protozoan parasite responsible for toxoplasmosis, which affects humans and animals. Serologic detection of anti-T. gondii immunoglobulins plays a crucial role in the clinical diagnosis of toxoplasmosis. In this work, a novel elect...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 19 July 2019Source: Veterinary ParasitologyAuthor(s): Juan Pablo Ek-Huchim, Isabel Jiménez-García, Rossanna Rodríguez-CanulAbstractMonogeneans Gyrodactylus von Nordmann 1832, cause outbreaks of gyrodactylosis in aquaculture settings worldwide. Detection of Gyrodactylus spp. is based on the morphological identification of isolated parasites after fish necropsy. Contributing to the diagnosis of gyrodactylosis, in this study, a non-destructive PCR assay was standardized; the PCR was first performed using genomic DNA of Gyrodactylus spp. isolated from the surface of the N...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
Authors: Greber UF Abstract Virus particles, 'virions', range in size from nano-scale to micro-scale. They have many different shapes and are composed of proteins, sugars, nucleic acids, lipids, water and solutes. Virions are autonomous entities and affect all forms of life in a parasitic relationship. They infect prokaryotic and eukaryotic cells. The physical properties of virions are tuned to the way they interact with cells. When virions interact with cells, they gain huge complexity and give rise to an infected cell, also known as 'virus'. Virion-cell interactions entail the processes of entry, replication and ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
The unnamed women, from Vietnam, had been suffering with eye pain before they went to the doctor and, according to reports, they may have encountered the parasites in rivers or streams.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: 15 October 2019Source: Sensors and Actuators B: Chemical, Volume 297Author(s): Tong Zhang, Xiang Ren, Dawei Fan, Xuan Kuang, Huan Wang, Dan Wu, Qin WeiAbstractProcalcitonin (PCT) is a kind of protein exists in the human blood. If the human bodies are infected with bacteria, fungi or parasites, the value of PCT in blood will be significantly raised. Thereby, we report an electrochemical immunosensor for measurement of PCT using gold nanoparticle (Au NP) decorated CeO2-CuO (CeO2-CuO-Au) as the platform and thionine modified Au@Ag heterojunction nanorods (Au@Ag-Th) as signal labels. Au NP decorated CeO2-CuO ...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: Available online 17 July 2019Source: Journal of Photochemistry and Photobiology B: BiologyAuthor(s): Sekar Vijayakumar, Balasubramanian Malaikozhundan, Kandasamy Saravanakumar, Esteban F. Durán-Lara, Myeong-Hyeon Wang, Baskaralingam VaseeharanAbstractFacile and low cost garlic clove extract based silver nanoparticles was synthesized and its broad spectrum of therapeutic activity including antibiofilm, antiparasitic and anti-breast cancer activity was evaluated. The synthesized garlic‑silver nanoparticles (G-AgNPs) were characterized by various physico-chemical techniques. G-AgNPs showed good opti...
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
This study describes the results of a farm-based welfare assessment, herd management, and some yield indicators in Northern Cyprus dairy goat farms. Out of 324 intensive milk goat farms which produce goats, only the 42 goat farms which had 7950 heads were chosen by random sampling in Northern Cyprus (2016), and face-to-face questionnaires and observations were conducted to collect data. Regarding the breeding techniques in these farms, of all the goats in these farms, 45.2% were cross-breed, 38.1% were Damascus, 11.9% were Saanen, and 4.8% were hair goats. The average of the total number of animals was 211.38  &plus...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
Nature, Published online: 19 July 2019; doi:10.1038/d41586-019-02203-5A one-two punch knocks out treatment-resistant strains of malaria.
Source: Nature AOP - Category: Research Source Type: research
We report the case of a 51-year-old man who received a heart transplantation and presented with a reactivation of the disease. The molecular characterization of the parasite showed that the reactivation was related to specific infection by a DTU I (TcISYL) parasite.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
Conclusions. Plasmodium falciparum malaria was characterized by depression of cellular and humoral immunity, the degree of which depended on the severity of the pathological process. PMID: 31308850 [PubMed]
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
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