Autoimmune heparin-induced thrombocytopenia and venous limb gangrene after aortic dissection repair: in vitro and in vivo effects of intravenous immunoglobulin.

CONCLUSION: Our clinical and laboratory observations support dose-dependent efficacy of IVIG for decreasing PLT activation and thus correcting thrombocytopenia in aHIT. Our case experience and literature review suggests dosing of 1 g/kg IVIG × 2 for patients with severe aHIT. PMID: 30903805 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30903805?dopt=Abstract

Source: Transfusion - March 22, 2019 Category: Hematology Authors: Arcinas LA, Manji RA, Hrymak C, Dao V, Sheppard JI, Warkentin TE Tags: Transfusion Source Type: research