(121) Pain, Sleep Disturbances, Fatigue, Mood Changes, and Underlying Inflammation: A Study of Patients with Chronic Low Back Pain (CLBP)

CLBP is a highly prevalent (55% adults) and expensive (costs range $84-$624.8 billion) condition in the United States. CLBP is accompanied by distressing behavioral symptoms, such as depressed mood, fatigue, and sleep disturbance, which negatively impact quality of life (QOL). The purpose of the study was to determine the extent to which behavioral symptoms (depressive mood, fatigue, poor sleep), independently or as a cluster, predict pain severity and QOL. Proinflammatory cytokine (IL-6) was evaluated to determine the extent to which inflammation may serve as a common underlying mechanism.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research