Controlling proteolysis of Clp peptidase: a possible target for combating mitochondrial diseases.

Controlling proteolysis of Clp peptidase: a possible target for combating mitochondrial diseases.
Int J Biochem Cell Biol. 2019 Mar 15;110:140-142
Authors: da Silva RR
Abstract
Some mechanisms of cellular stress, aging, and apoptosis are related to proteolysis. With respect to ClpP, little is known about the mechanical manner in which the substrate is hydrolyzed in and released from the degradation chamber. Furthermore, what would be the real influence of ClpP in mammalian UPRmt?
PMID: 30885675 [PubMed - as supplied by publisher]

Source: The International Journal of Biochemistry and Cell Biology - March 14, 2019 Category: Biochemistry Authors: da Silva RR Tags: Int J Biochem Cell Biol Source Type: research