Early detection of colorectal cancer based on presence of methylated syndecan-2 (SDC2) in stool DNA.

CONCLUSIONS: Results of this study validated the capability of stool DNA based-SDC2 methylation test by LTE-qMSP for early detection of CRC patient with high specificity. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03146520 , Registered 10 May 2017, Retrospectively registered; however, control arm was prospectively registered. PMID: 30876480 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30876480?dopt=Abstract

Source: Clinical Colorectal Cancer - March 14, 2019 Category: Cancer & Oncology Authors: Han YD, Oh TJ, Chung TH, Jang HW, Kim YN, An S, Kim NK Tags: Clin Epigenetics Source Type: research