Trends in Renal Function among Heart-Transplant Recipients of Donor-Derived Hepatitis C Virus

Donor-derived hepatitis C infection (dd-HCV) infection may increase risk of renal impairment (RI) among heart transplant (HT) recipients. Sofosbuvir, an integral component of anti-HCV direct-acting antivirals (DAAs), has also been linked to RI. To date, no prior study has examined the trends in renal function for HT recipients of dd-HCV infection, and assessed safety and efficacy of sofosbuvir-based DAAs.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: S. Zalawadiya, J. Lindenfeld, A. Shah, M. Wigger, M. Danter, D. Brinkley, J. Menachem, L. Punnoose, S. Brown Sacks, H. Ooi, K. Balsara, R. Perri, J. Awad, S. Smith, R. Fowler, H. O'Dell, C. Darragh, S. Ruzevich-Scholl, K. Schlendorf Tags: 98 Source Type: research