Accelerated Cardiac Allograft Vasculopathy: A Clinical and Pathologic Correlation Study

Cardiac allograft vasculopathy (CAV) is a prevalent cause of graft failure and has remained so despite advances in HLA matching and immunosuppression in recent decades. Several distinct pathologic phenotypes of CAV have been described (Lu et al JHLT 2011 and Huibers et al Atherosclerosis 2014), but the correlation of these phenotypes to clinical features has been limited. Of particular interest in this study are patients who develop accelerated CAV, since this presentation is so clinically devastating but also because it may provide important mechanistic insights into CAV initiation and progression.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: 120 Source Type: research