Sub-Normothermic Ex-Vivo Lung Perfusion Attenuates Ischemia Reperfusion Injury from Donation after Circulatory Death Donors

Evaluation of a potential lung graft in an ex-vivo lung perfusion (EVLP) system has gained an increased use among transplantation centers. Current standard of organ assessment before transplantation with machine perfusion are performed with normothermic temperature but sub-normothermic setting is under clinical use among several solid organs. Our aim was to investigate the impact of sub-normothermic EVLP from donation after circulatory death donor lungs in a rat model.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: T. Maeyashiki, S. Arni, I. Iskender, W. Weder, I. Inci Tags: 573 Source Type: research