The reconstructed natural history of type 1 diabetes mellitus

The reconstructed natural history of type 1 diabetes mellitusThe reconstructed natural history of type 1 diabetes mellitus, Published online: 11 March 2019; doi:10.1038/s41574-019-0192-8The causes of type 1 diabetes mellitus (T1DM) are unclear; however, a general consensus exists that T1DM is a T cell-mediated autoimmune disease characterized by the selective destruction of insulin-secreting β-cells. Now, two imaging mass cytometry studies of human pancreatic tissue illuminate new biology in the pathogenesis of T1DM.
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research