Repeated fluoxetine treatment induces long-lasting neurotrophic changes in the medial prefrontal cortex of adult rats.

In conclusion, repeated Flx treatment, with the paradigm used, induces long-lasting neuroplastic changes in the mPFC of normal adult rats, and such changes and related behavioral manifestations may persist up to 20 days after the last dose. PMID: 30849415 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30849415?dopt=Abstract

Source: Behavioural Brain Research - March 4, 2019 Category: Neurology Authors: Song T, Wu H, Li R, Xu H, Rao X, Gao L, Zou Y, Lei H Tags: Behav Brain Res Source Type: research