A Small Fish Model for Quantitative Analysis of Radiation Effects Using Visualized Thymus Responses in GFP Transgenic Medaka.

CONCLUSION: A biomonitoring system to detect the effects of radiation in real time was established. Using this system, the threshold doses for the induction of thymic atrophy by acute X-rays and Fe ions were 2-5 Gy and 0.5-1 Gy, respectively. The Relative Biological Effectiveness (RBE) of Fe-ion to X-rays was estimated to be around 3. This system may be used to evaluate the risk from concurrent exposure to hazards, such as chemicals and radiation, and for aging research.
PMID: 30822211 [PubMed - as supplied by publisher]

Source: International Journal of Radiation Biology - March 4, 2019 Category: Radiology Tags: Int J Radiat Biol Source Type: research