Systematic literature review on the economic, humanistic, and societal burden of heart failure in children and adolescents.

Systematic literature review on the economic, humanistic, and societal burden of heart failure in children and adolescents. Expert Rev Pharmacoecon Outcomes Res. 2019 Feb 12;: Authors: Burch M, Nallagangula TK, Lochlainn EN, Severin T, Thakur L, Jaecklin T, George AT, Solar-Yohay S, Rossano JW, Shaddy RE Abstract INTRODUCTION: Unlike the adult heart failure (HF) patient population, there is scarce of information on the overall burden of HF in the pediatric population across geographies and within different age groups. Areas covered: A systematic review aims to describe and quantify the economic, humanistic, and societal burden of pediatric (age <18 years) HF on patients and caregivers. Eighteen published studies over a period of 10-years (Jan 1st 2006- May 20th 2016) were identified through Embase, Medline, Cochrane Library and selected congresses. Studies from the US reported higher HF-related hospitalization-rates in infants aged <1 year (49.3%-63.9%) versus children aged 1-12 years (18.7%-30.9%) in HF diagnosed patients. Across the studies, average length of hospital-stay was 15 days, increasing to 26 days for infants. Average annual hospital charges were higher for infants (US$176,000) versus children aged 1-10 years (US$132,000) in the US. In Germany, diagnosis-related group (DRG)-based hospital-allowances per HF-case increased from €3,498 in 1995 to €4,250 in 2009. Expert opinion: To our knowledge, this is the first s...
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research