Clinical Experience With the Use of Doxycycline and Ursodeoxycholic Acid for the Treatment of Transthyretin Cardiac Amyloidosis
Transthyretin cardiac amyloidosis (ATTR CA) is characterized by extracellular myocardial deposition of amyloid fibrils derived from either wild-type or mutant forms of the transthyretin protein (TTR).1 –3 ATTR CA represents an important cause of progressive heart failure which is now increasingly recognized with improved modern diagnostic strategies.4 Previously, treatment options for ATTR CA were limited to supportive care, with the possibility of cardiac transplantation for a small number of e ligible patients with advanced heart failure.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Erin Karlstedt, Victor Jimenez-Zepeda, Jonathan G. Howlett, James A. White, Nowell M. Fine Source Type: research
More News: Amyloidosis | Cardiology | Doxycycline | Heart | Heart Failure | Heart Transplant | Transplants