Medical and endovascular treatments of symptomatic intracranial stenosis. A Bayesian network meta-analysis
Publication date: Available online 8 February 2019Source: Journal of Clinical NeuroscienceAuthor(s): S. Vidale, E. Agostoni, G. Grampa, A. Consoli, D. ConsoliAbstractIntracranial stenosis is a well-established stroke risk factor with an increase of stroke recurrence or TIA up to 12.6% at 1 year. Treatments are different: medical and endovascular. We performed a multiple treatment comparison analysis to detect the best treatment in reducing the risk of stroke recurrence. We searched in Medline, Embase, Cochrane Central Register of Controlled Trials databases between 1979 and October 2017. Inclusion criteria were prospective randomized trials that evaluated patients with TIA or stroke due to intracranial stenosis and treated with different medical therapies and/or endovascular procedures. Primary endpoint was the recurrence of TIA or stroke in the territory of intracranial stenosis, while secondary endpoint was represented by any stroke or vascular death. Multiple treatment comparison meta-analysis based on a Bayesian fixed and random effects Poisson model was performed. Seven trials were included with a total of 1337 patients. At multiple treatment comparison, no significant differences between treatments were observed for both primary (median fixed effect standard OR: 0.40; 95%CI: 0.02–1.07) and secondary endpoints (median random effect standard OR: 1.17; 95%CI: 0.32–1.92). Treatment with aspirin alone ranked with high values both for primary and secondary endpo...
The objectives of this study were to evaluate the effects of community-based walking training (CWT) on the walking ability and fall-related self-efficacy of chronic stroke patients and compare the effects of CWT to the conventional walking programs in stro...
In pediatric stroke, advanced neuroimaging may be utilized to characterize tissue viability and recovery potential.Stroke
Rebecca Leigh, of Maryland, had been filming yoga tutorials for 26,000 social media fans. She now has daily headaches, memory loss and struggles with speech.
(MedPage Today) -- Findings from post hoc analysis of WAKE-UP trial could complicate ED imaging strategy
Condition: Stroke Interventions: Device: 1x1 anodal tDCS; Device: Sham tDCS; Behavioral: Robotic Rehabilitation Sponsor: University of Calgary Recruiting
Condition: Stroke, Acute Intervention: Device: tDCS Sponsor: University Hospital of Liege Recruiting
Condition: Stroke Intervention: Device: Luna EMG Sponsor: Rehamed Center Not yet recruiting
Conditions: Complex Regional Pain Syndromes; Fibromyalgia; Stroke; Traumatic Brain Injury; Osteoarthritis; Back Pain; Sciatica Intervention: Device: Virtual Environment Biofeedback Sponsor: Cambridge University Hospitals NHS Foundation Trust Enrolling by invitation
Condition: Non-valvular Atrial Fibrillation (NVAF) Intervention: Drug: Rivaroxaban (Xarelto,Bay 59-7939) Sponsors: Bayer; Janssen Research & Development, LLC Not yet recruiting
Climate change is in the news more and more, and the projections from virtually all of the world’s climate scientists are becoming increasingly dire. Almost daily, we are confronted with images of extreme weather patterns, disease outbreaks, and the loss of certain species. It is almost biblical in proportion. Most poignant, to me, are the distressing images of starving, displaced polar bears whose icy habitats are melting away. Many of the things that we can do to prevent or slow climate change are intuitive, difficult as they may be to put into practice: conserve energy, drive less, elect politicians that are dedic...