Conditioning electrical stimulation promotes functional nerve regeneration.

In this study, we found that CES improved nerve regeneration and reinnervation well beyond that of CCL. Specifically, compared to CCL, CES resulted in greater intraepidermal skin and NMJ reinnervation, and greater physiological and functional recovery including mechanosensation, compound muscle action potential on nerve conduction studies, normalization of gait pattern, and motor performance on the horizontal ladder test. These findings have direct clinical relevance as CES could be delivered at the bedside before scheduled nerve surgery. PMID: 30731076 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30731076?dopt=Abstract

Source: Experimental Neurology - February 4, 2019 Category: Neurology Authors: Senger JL, Chan KM, Macandili H, Chan AWM, Verge VMK, Jones KE, Webber CA Tags: Exp Neurol Source Type: research