Increasing multidrug and fluoroquinolone resistance among Salmonella Typhi from sporadic outbreaks in Kenya

Purpose: Background: Typhoid fever (TF) caused by Salmonella Typhi remains a major public health problem in Kenya. A systematic surveillance in two slum areas in Nairobi, revealed a crude incidence of TF of 247 cases per 100,000 person-years of observation (pyo), with highest rates in children 5 –9 years old (596 per 100,000pyo). Currently over a third of S. Typhi isolates are multidrug-resistant (MDR), and show reduced susceptibility to Fluoroquinolones; the drugs of choice for treatment of MDR cases.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 20.017 Source Type: research