Ovarian tissue cryopreservation for patients with premature ovary insufficiency caused by cancer treatment: optimal protocol.

CONCLUSIONS: OT cryopreserved and thawed in medium supplemented with 5 mM NAC shows the highest antioxidant and lowest ROS capability, good apoptotic parameters, and follicle viability. Our results need to be confirmed in larger patient cohorts prior to being accepted as a standard protocol.
PMID: 30676094 [PubMed - as supplied by publisher]

Source: Climacteric - January 24, 2019 Category: Geriatrics Authors: Li Y, Ruan X, Liebenthron J, Montag M, Zhou Q, Kong W, Du J, Jin F, Li S, Cheng J, Wang H, Mueck AO Tags: Climacteric Source Type: research