Ipsilateral cortical silent period as a marker of corpus callosum function in amyotrophic lateral sclerosis

Background: New imaging techniques suggest an involvement of the motor corpus callosum (CC) in amyotrophic lateral sclerosis (ALS) (Agosta et al., 2010; Unrath et al., 2011; Kassubek et al., 2012). Yet, a functional involvement can not easily be shown only by the means of magnetic resonance imaging or fibre tracking. Our goal was to demonstrate functional deficits of the motor CC in ALS using transcranial magnetic stimulation (TMS).

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: A. H übers, B. Böckler, T. Kammer Source Type: research