Salvage high-intensity focused ultrasound versus salvage radical prostatectomy for radiation-recurrent prostate cancer: a comparative study of oncological, functional, and toxicity outcomes

ConclusionS-HIFU and S-RP could both be considered valuable LST options for patients with radiation-recurrent nonmetastatic PCa with sufficient life expectancy. S-RP is associated with more pad-dependent patients at 12  months.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research

Related Links:

This study aimed to validate a predictive model for late FI by Rancati et al.2
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Comment Source Type: research
ConclusionsCurrent evidence is weak and limited to a few retrospective series. Oncological control is acceptable although it seems lower compared to a primary treatment setting. Functional outcomes are comparable to primary treatment with the exception of EF; overall, suggesting FT has little impact on subsequent salvage treatments. Future studies are needed to confirm the current findings.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Conclusions: Patients receiving HDR brachytherapy had lower acute urinary and rectal toxicity compared to the patients receiving LDR, even when combined with EBRT. However, long-term toxicity was similar. PMID: 30662471 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
ConclusionsFocal cryotherapy primarily for anterior intermediate and high-risk prostate cancer results in good rates of cancer control and low rates of treatment-related side effects.Patient summaryIn this multicentre study of 122 patients undergoing focal cryotherapy for medium- to high-risk prostate cancer, at 3 yr, no patient died from their cancer whilst failure-free survival, was approximately 90%. None of the patients needed pads for managing urine leakage, although 16% had erection problems.
Source: European Urology - Category: Urology & Nephrology Source Type: research
Conclusion: A Martius flap and additional fascial sling could be successfully used to optimize DUF treatment.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusion: A Martius flap and additional fascial sling could be successfully used to optimize DUF treatment.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Stress urinary incontinence is common in men after prostate cancer surgery. Rehabilitative interventions incorporate pelvic floor muscle training, biofeedback, electrical stimulation, lifestyle changes, or a combination of these strategies. However, little is known about the physiological impact of whole-body vibration for stress urinary incontinence after radical prostatectomy.
Source: Physiotherapy - Category: Physiotherapy Authors: Source Type: research
Urologic disease is a major contributor to morbidity and health care costs in the United States. A recent National Health and Nutrition Examination Survey indicates the prevalence of kidney stones among US adults has risen to 10%, and it is estimated that some degree of urinary incontinence affects 30% of the population.1 According to Surveillance, Epidemiology, and End Results estimates 11.2% of US adults will be diagnosed with prostate cancer, 2.3% with bladder cancer, and 1.7% with kidney cancer over their lifetime.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
ConclusionsThe crosswalks are a valid way to convert between sexual and urinary domains of the MSK and EPIC-26 instruments.Patient summaryWe developed and validated a set of formulas that allow conversion of sexual and urinary function scores between the Memorial Sloan Kettering and Expanded Prostate Cancer Index Composite Short Form patient-reported outcome questionnaires. These crosswalks allow seamless transition between the two questionnaires.
Source: European Urology - Category: Urology & Nephrology Source Type: research
CONCLUSIONS: Despite anterior reconstruction of the puboprostatic ligament showed no significant effect on the overall continence, it showed earlier return to continence up to 6 months, which supports the theory that anterior puboprostatic reconstruction may provide better immediate continence and shorten the time to continence for RALP patients. However, most of the published literature showed better continence rates with the total anatomical reconstruction (combined anterior and posterior). Therefore, we started to offer patients in our center total anatomical reconstruction during RALP. PMID: 30547904 [PubMed - as s...
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
More News: Brachytherapy | Cancer | Cancer & Oncology | External Beam Therapy | High Intensity Focused Ultrasound Therapy | Incontinence | Prostate Cancer | Prostatectomy | Radiation Therapy | Study | Toxicology | Ultrasound | Urology & Nephrology